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Rapamycin was shown in a mouse model of Parkinson’s to preserve glutamate transporter function, keeping glutamate at the right levels.[ref] Glutamate receptors: The availability of glutamate receptors is the other half of the picture for both stimulation of the neurons and good brain function – as well as for removing glutamate from the synapse

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Different carriers can enhance the pharmacodynamics and stability, and reduce toxicity of the active peptide, such as liposome encapsulation or the use of peptoids, the D-conformation-based peptide and β-peptides (Sajjan et al., 2001